Definitions for jumonji domain-containing histone demethylases

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U.S. National Library of Medicine

  1. Jumonji Domain-Containing Histone Demethylases

    A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.

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