What does janus kinases mean?

Definitions for janus kinases
janus ki·nas·es

This dictionary definitions page includes all the possible meanings, example usage and translations of the word janus kinases.


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Wikipedia

  1. janus kinases

    Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially named "just another kinase" 1 and 2 (since they were just two of many discoveries in a PCR-based screen of kinases), but were ultimately published as "Janus kinase". The name is taken from the two-faced Roman god of beginnings, endings and duality, Janus, because the JAKs possess two near-identical phosphate-transferring domains. One domain exhibits the kinase activity, while the other negatively regulates the kinase activity of the first.

U.S. National Library of Medicine

  1. Janus Kinases

    A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.

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Numerology

  1. Chaldean Numerology

    The numerical value of janus kinases in Chaldean Numerology is: 9

  2. Pythagorean Numerology

    The numerical value of janus kinases in Pythagorean Numerology is: 8

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"janus kinases." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/janus+kinases>.

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