1. (noun) irritation, annoyance, vexation, botheration
the psychological state of being irritated or annoyed
2. (noun) pique, temper, irritation
a sudden outburst of anger
"his temper sparked like damp firewood"
3. (noun) irritation
(pathology) abnormal sensitivity to stimulation
"any food produced irritation of the stomach"
4. (noun) excitation, innervation, irritation
the neural or electrical arousal of an organ or muscle or gland
5. (noun) discomfort, soreness, irritation
an uncomfortable feeling of mental painfulness or distress
6. (noun) aggravation, irritation, provocation
unfriendly behavior that causes anger or resentment
7. (noun) annoyance, annoying, irritation, vexation
the act of troubling or annoying someone
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Definition of 'irritation' 
