Definitions for iridocorneal endothelial syndrome

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  1. Iridocorneal endothelial syndrome

    Iridocorneal endothelial or ICE syndrome is a spectrum of conditions of the eye, where the inner layer of the cornea appears abnormal. It includes Cogan-Reese syndrome, Chandler's syndrome, and progressive iris atrophy. "Cogan-Reese syndrome" is named for David Glendenning Cogan and Algernon Reese.

U.S. National Library of Medicine

  1. Iridocorneal Endothelial Syndrome

    A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.

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