Definitions for iopanoic acid

This page provides all possible meanings and translations of the word iopanoic acid

FreebaseRate this definition:(0.00 / 0 votes)

  1. Iopanoic acid

    Iopanoic acid is an iodine-containing radiocontrast medium used in cholecystography. Both iopanoic acid and ipodate sodium are potent inhibitors of thyroid hormone release from thyroid gland, as well as of peripheral conversion of thyroxine to triiodothyronine. These compounds inhibit 5'deiodinase enzymes, which catalyse T4-T3 conversion in the thyroid cell, liver, kidney, skeletal muscle, heart, brain, pituitary. This accounts for the dramatic improvement in both subjective and objective symptoms of hyperthyroidism, particularly when they are used as an adjunctive therapy with thioamides. These are less toxic, as iodine is covalently bound in these compounds. They can be used in the treatment of patients with severe thyrotoxicosis and significant morbidity for rapid control of elevated plasma triiodothyronine concentrations. The use of iopanoic acid for treatment of thyrotoxicosis has been discontinued in the United States. In addition to inhibiting deiodinase enzymes, iopanoic acid is also a substrate of type 1 deiodinase. Iopanoic acid underwent monodeiodination in the presence of type 1 deiodinase in a microsomal mouse liver preparation.

U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)

  1. Iopanoic Acid

    Radiopaque medium used as diagnostic aid.


Find a translation for the iopanoic acid definition in other languages:

Select another language:

Discuss these iopanoic acid definitions with the community:

Word of the Day

Would you like us to send you a FREE new word definition delivered to your inbox daily?

Please enter your email address:     


Use the citation below to add this definition to your bibliography:


"iopanoic acid." STANDS4 LLC, 2015. Web. 31 Mar. 2015. < acid>.

Are we missing a good definition for iopanoic acid? Don't keep it to yourself...

The Web's Largest Resource for

Definitions & Translations

A Member Of The STANDS4 Network

Nearby & related entries:

Alternative searches for iopanoic acid:

Thanks for your vote! We truly appreciate your support.