What does inhibitory mean?
Definitions for inhibitory
in·hibito·ry
This dictionary definitions page includes all the possible meanings, example usage and translations of the word inhibitory.
Princeton's WordNet
inhibitory, repressive, repressingadjective
restrictive of action
"a repressive regime"; "an overly strict and inhibiting discipline"
Wiktionary
inhibitoryadjective
that inhibits
inhibitoryadjective
of, or relating to an inhibitor
Wikipedia
inhibitory
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential. IPSP were first investigated in motorneurons by David P. C. Lloyd, John Eccles and Rodolfo Llinás in the 1950s and 1960s. The opposite of an inhibitory postsynaptic potential is an excitatory postsynaptic potential (EPSP), which is a synaptic potential that makes a postsynaptic neuron more likely to generate an action potential. IPSPs can take place at all chemical synapses, which use the secretion of neurotransmitters to create cell to cell signalling. Inhibitory presynaptic neurons release neurotransmitters that then bind to the postsynaptic receptors; this induces a change in the permeability of the postsynaptic neuronal membrane to particular ions. An electric current that changes the postsynaptic membrane potential to create a more negative postsynaptic potential is generated, i.e. the postsynaptic membrane potential becomes more negative than the resting membrane potential, and this is called hyperpolarisation. To generate an action potential, the postsynaptic membrane must depolarize—the membrane potential must reach a voltage threshold more positive than the resting membrane potential. Therefore, hyperpolarisation of the postsynaptic membrane makes it less likely for depolarisation to sufficiently occur to generate an action potential in the postsynaptic neurone. Depolarization can also occur due to an IPSP if the reverse potential is between the resting threshold and the action potential threshold. Another way to look at inhibitory postsynaptic potentials is that they are also a chloride conductance change in the neuronal cell because it decreases the driving force. This is because, if the neurotransmitter released into the synaptic cleft causes an increase in the permeability of the postsynaptic membrane to chloride ions by binding to ligand-gated chloride ion channels and causing them to open, then chloride ions, which are in greater concentration in the synaptic cleft, diffuse into the postsynaptic neuron. As these are negatively charged ions, hyperpolarisation results, making it less likely for an action potential to be generated in the postsynaptic neuron. Microelectrodes can be used to measure postsynaptic potentials at either excitatory or inhibitory synapses. In general, a postsynaptic potential is dependent on the type and combination of receptor channel, reverse potential of the postsynaptic potential, action potential threshold voltage, ionic permeability of the ion channel, as well as the concentrations of the ions in and out of the cell; this determines if it is excitatory or inhibitory. IPSPs always want to keep the membrane potential more negative than the action potential threshold and can be seen as a "transient hyperpolarization". EPSPs and IPSPs compete with each other at numerous synapses of a neuron. This determines whether or not the action potential at the presynaptic terminal regenerates at the postsynaptic membrane. Some common neurotransmitters involved in IPSPs are GABA and glycine.
ChatGPT
inhibitory
Inhibitory refers to something that slows down, restrains, blocks, or suppresses a process, behavior, or response. It is often used in biological and physiological contexts such as in reference to neurons, synapses, or substances that inhibit or reduce activity. However, it can also be used in a broader sense in any context where a process or action is hindered or restricted.
Webster Dictionary
Inhibitoryadjective
of or pertaining to, or producing, inhibition; consisting in inhibition; tending or serving to inhibit; as, the inhibitory action of the pneumogastric on the respiratory center
Etymology: [LL. inhibitorius: cf. F. inhibitoire.]
Numerology
Chaldean Numerology
The numerical value of inhibitory in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of inhibitory in Pythagorean Numerology is: 3
Examples of inhibitory in a Sentence
So many people say to themselves, ‘It’s just me. I’ve got a problem.’ But actually, HSDD may be how your brain is wired, the biology is telling us there’s increased activation of inhibitory areas in the brain — the same areas that tell us it’s not OK to walk around in public naked — and those areas are switching off sexual desire. How can we tackle that? We give a hormone that would naturally give you increased sexual desire, essentially hijacking the normal system.
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Translations for inhibitory
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"inhibitory." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/inhibitory>.
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