What does infliximab mean?

Definitions for infliximab
in·flix·imab

This dictionary definitions page includes all the possible meanings, example usage and translations of the word infliximab.

Princeton's WordNet

  1. infliximab, Remicadenoun

    a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician

  2. infliximab, Remicadenoun

    an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis

Wiktionary

  1. infliximabnoun

    A chimeric monoclonal antibody used to treat autoimmune disorders.

Wikipedia

  1. Infliximab

    Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, and Behçet's disease. It is given by slow injection into a vein, typically at six- to eight-week intervals.Common side effects include infections, acute infusion reactions, and abdominal pain. Infliximab is a chimeric monoclonal antibody biologic. It seems to work by binding to and neutralizing TNF-α, preventing it from interacting with its receptors on the cell. TNF-α is a chemical messenger (cytokine) and a key part of the autoimmune reaction. Infliximab was originally developed in mice as a mouse antibody. Because humans have immune reactions to mouse proteins, the mouse common domains were replaced with similar human antibody domains. They are monoclonal antibodies and have identical structures and affinities to the target. Because they are a combination of mouse and human antibody amino acid sequences, they are called a "chimeric monoclonal antibody".Infliximab was approved for medical use in the United States in 1998, and in the European Union in August 1999. Infliximab biosimilars have been approved in the EU (2013), in Japan (2014), and in the United States (2016, 2017, 2019). It is on the World Health Organization's List of Essential Medicines.

ChatGPT

  1. infliximab

    Infliximab is a type of medication classified as a monoclonal antibody, which is used to treat various conditions such as rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis and ulcerative colitis. It works by blocking the action of a protein in the body's immune system that causes inflammation.

Wikidata

  1. Infliximab

    Infliximab is a monoclonal antibody against tumour necrosis factor alpha used to treat autoimmune diseases. Remicade is marketed by Janssen Biotech, Inc. in the USA, Mitsubishi Tanabe Pharma in Japan, Xian Janssen in China, and Schering-Plough elsewhere. Infliximab was approved by the U.S. Food and Drug Administration for the treatment of psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab won its initial approval by the FDA for the treatment of Crohn's disease in August 1998. Infliximab works by binding to TNF-α. TNF-α is a chemical messenger and a key part of the autoimmune reaction. In rheumatoid arthritis, infliximab seems to work by preventing TNF-α from binding to its receptor in the cell. Infliximab is an artificial antibody. It was originally developed in mice as a mouse antibody. Because humans have immune reactions to mouse proteins, the mouse common domains were replaced with similar human antibody domains. Because the antibodies were produced from one cell grown into a clone of identical cells, it is called a monoclonal antibody. Furthermore, as a combination of mouse and human antibody amino acid sequences, it is called a chimeric monoclonal antibody.

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Numerology

  1. Chaldean Numerology

    The numerical value of infliximab in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of infliximab in Pythagorean Numerology is: 9

Popularity rank by frequency of use

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"infliximab." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/infliximab>.

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