Definitions of immunoglobulin j-chains

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Definition of 'immunoglobulin j-chains'

U.S. National Library of Medicine

1. immunoglobulin j-chains
A 15 kD "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.

'immunoglobulin j-chains' - Nearby Entries
immunoglobulin idiotypes immunoglobulin isotypes immunoglobulin j recombination signal sequence-binding protein immunoglobulin j-chains immunoglobulin joining region immunoglobulin kappa-chains immunoglobulin km allotypes

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