Definitions of immunoglobulin idiotypes

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Definition of 'immunoglobulin idiotypes'

U.S. National Library of Medicine

1. immunoglobulin idiotypes
Unique, genetically controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.

'immunoglobulin idiotypes' - Nearby Entries
immunoglobulin gamma-chains immunoglobulin gm allotypes immunoglobulin heavy chains immunoglobulin idiotypes immunoglobulin isotypes immunoglobulin j recombination signal sequence-binding protein immunoglobulin j-chains

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