Definitions of immunoglobulin class switching

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Definition of 'immunoglobulin class switching'

U.S. National Library of Medicine

1. immunoglobulin class switching
Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.

'immunoglobulin class switching' - Nearby Entries
immunoglobulin a, secretory immunoglobulin allotypes immunoglobulin alpha-chains immunoglobulin class switching immunoglobulin constant regions immunoglobulin delta-chains immunoglobulin epsilon-chains

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