What does imipenem mean?

Definitions for imipenem
imipen·em

This dictionary definitions page includes all the possible meanings, example usage and translations of the word imipenem.


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Wiktionary

  1. imipenemnoun

    A broad-spectrum beta-lactam antibiotic

Wikipedia

  1. Imipenem

    Imipenem (trade name Primaxin among others) is an intravenous β-lactam antibiotic discovered by Merck scientists Burton Christensen, William Leanza, and Kenneth Wildonger in the mid-1970s. Carbapenems are highly resistant to the β-lactamase enzymes produced by many multiple drug-resistant Gram-negative bacteria, thus play a key role in the treatment of infections not readily treated with other antibiotics.Imipenem was patented in 1975 and approved for medical use in 1985. It was discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Thienamycin has antibacterial activity, but is unstable in aqueous solution, so impractical to administer to patients. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species. It is not active against MRSA, however.

Wikidata

  1. Imipenem

    Imipenem is an intravenous β-lactam antibiotic developed in 1980. It has an extremely broad spectrum of activity. Imipenem belongs to the subgroup of carbapenems. It is derived from a compound called thienamycin, which is produced by the bacterium Streptomyces cattleya. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species. It is not active against MRSA, however. Imipenem and other drugs in the carbapenem class are typically restricted in use, to avoid widespread bacterial resistance.

U.S. National Library of Medicine

  1. Imipenem

    Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.

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Numerology

  1. Chaldean Numerology

    The numerical value of imipenem in Chaldean Numerology is: 6

  2. Pythagorean Numerology

    The numerical value of imipenem in Pythagorean Numerology is: 3

Popularity rank by frequency of use

imipenem#100000#125993#333333

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"imipenem." Definitions.net. STANDS4 LLC, 2024. Web. 19 Mar. 2024. <https://www.definitions.net/definition/imipenem>.

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