What does ibalizumab mean?
Definitions for ibalizumab
ibal·izum·ab
This dictionary definitions page includes all the possible meanings, example usage and translations of the word ibalizumab.
Wiktionary
ibalizumabnoun
A nonimmunosuppressive monoclonal antibody being investigated as an HIV entry inhibitor.
Wikipedia
Ibalizumab
Ibalizumab, sold under the brand name Trogarzo, is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell. Post-attachment inhibitors are a subclass of HIV drugs called entry inhibitors. On March 6, 2018, the U.S. Food and Drug Administration (FDA) approved ibalizumab for multidrug-resistant HIV-1. It is used in combination with other antiretroviral drugs. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.
Wikidata
Ibalizumab
Ibalizumab is a non-immunosuppressive monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits the viral entry process. It is being investigated as an HIV entry inhibitor with the ability to block both CCR5- and CXCR4-tropic viruses, and is currently undergoing a Phase II clinical trial with an estimated study completion date in December 2010. Specific Research is also conducted at the Aaron Diamond AIDS Research Center under the direction of David Ho. Results from a previous Phase II of ibalizumab, reported by the original developer Tanox in 2006, showed that HIV-infected patients who received the drug, in combination with an optimized background regimen, maintained a considerably greater reduction in viral load and experienced a statistically significant increase in CD4+ cells than did patients given placebo in combination with OBR. Thus, pending results of further trials, it is presently one of a limited number of viable alternative strategies to contain the virus without recourse to antiretroviral drug cocktails or a vaccine.
Numerology
Chaldean Numerology
The numerical value of ibalizumab in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of ibalizumab in Pythagorean Numerology is: 6
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"ibalizumab." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/ibalizumab>.
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