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1. (n.) hemochromatosis
a disorder of iron metabolism manifested by bronzed skin due to excessive iron absorption, leading to joint pain, diabetes, and liver damage if iron concentration is not reduced.
Etymology: (1895–1900; hemo-+ Gk
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| Definition of 'hemochromatosis' |
Princeton's WordNet |
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1. (noun) hemochromatosis, iron-storage disease, iron overload, bronzed diabetes
pathology in which iron accumulates in the tissues; characterized by bronzed skin and enlarged liver and diabetes mellitus and abnormalities of the pancreas and the joints
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| Definition of 'hemochromatosis' |
U.S. National Library of Medicine |
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1. hemochromatosis
A disorder due to the deposition of hemosiderin in the parenchymal cells, causing tissue damage and dysfunction of the liver, pancreas, heart, and pituitary. Full development of the disease in women is restricted by menstruation, pregnancy, and lower dietary intake of iron. Acquired hemochromatosis may be the result of blood transfusions, excessive dietary iron, or secondary to other disease. Idiopathic or genetic hemochromatosis is an autosomal recessive disorder of metabolism associated with a gene tightly linked to the A locus of the HLA complex on chromosome 6. (From Dorland, 27th ed)
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