Definitions for haemophilia

This page provides all possible meanings and translations of the word haemophilia

Princeton's WordNet

  1. hemophilia, haemophilia, bleeder's disease(noun)

    congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son

Wiktionary

  1. haemophilia(Noun)

    Any of several hereditary illnesses that impair the body's ability to control bleeding, usually passed from mother to son.

  2. Origin: Medical term; from αἷμα (blood) + φιλία (friendship)

Freebase

  1. Haemophilia

    Haemophilia is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation, which is used to stop bleeding when a blood vessel is broken. Haemophilia A is the most common form of the disorder, present in about 1 in 5,000–10,000 male births. Haemophilia B occurs in around 1 in about 20,000–34,000 male births. Like most recessive sex-linked, X chromosome disorders, haemophilia is more likely to occur in males than females. This is because females have two X chromosomes while males have only one, so the defective gene is guaranteed to manifest in any male who carries it. Because females have two X chromosomes and haemophilia is rare, the chance of a female having two defective copies of the gene is very remote, so females are almost exclusively asymptomatic carriers of the disorder. Female carriers can inherit the defective gene from either their mother or father, or it may be a new mutation. Although it is not impossible for a female to have haemophilia, it is unusual: a female with haemophilia A or B would have to be the daughter of both a male haemophiliac and a female carrier, while the non-sex-linked haemophilia C due to coagulant factor XI deficiency, which can affect either sex, is more common in Jews of Ashkenazi descent but rare in other population groups.

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