In enzymology, a guanylate kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and GMP, whereas its two products are ADP and GDP. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups with a phosphate group as acceptor. This enzyme participates in purine metabolism. Guanylate kinase catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. In prokaryotes, lower eukaryotes and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids. GK has been shown to be structurally similar to protein A57R from various strains of Vaccinia virus.
U.S. National Library of Medicine
Catalyzes the ATP-dependent PHOSPHORYLATION of GMP to generate GDP and ADP.
The numerical value of guanylate kinase in Chaldean Numerology is: 1
The numerical value of guanylate kinase in Pythagorean Numerology is: 3
Images & Illustrations of guanylate kinase
Find a translation for the guanylate kinase definition in other languages:
Select another language:
Discuss these guanylate kinase definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"guanylate kinase." Definitions.net. STANDS4 LLC, 2017. Web. 27 Apr. 2017. <http://www.definitions.net/definition/guanylate kinase>.