Definitions for guanosine triphosphate

This page provides all possible meanings and translations of the word guanosine triphosphate

Random House Webster's College Dictionary

gua′nosine triphos′phate(n.)

  1. Category: Biochemistry

    Ref: See GTP.


  1. Guanosine triphosphate

    Guanosine-5'-triphosphate is a purine nucleoside triphosphate. It can act as a substrate for the synthesis of RNA during the transcription process or DNA during DNA replication. Its structure is similar to that of the guanine nucleobase, the only difference being that nucleotides like GTP have a ribose sugar and three phosphates, with the nucleobase attached to the 1' and the triphosphate moiety attached to the 5' carbons of the ribose. It also has the role of a source of energy or an activator of substrates in metabolic reactions, like that of ATP, but more specific. It is used as a source of energy for protein synthesis and gluconeogenesis. GTP is essential to signal transduction, particularly with G-proteins, in second-messenger mechanisms where it is converted to guanosine diphosphate through the action of GTPases.

U.S. National Library of Medicine

  1. Guanosine Triphosphate

    Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.


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