Definitions for guanidineˈgwæn ɪˌdin, -dɪn, ˈgwɑ nɪ-
This page provides all possible meanings and translations of the word guanidine
Random House Webster's College Dictionary
guan•i•dineˈgwæn ɪˌdin, -dɪn, ˈgwɑ nɪ-(n.)
a crystalline, alkaline, water-soluble solid, CH5N3, used in making plastics, resins, and explosives.
Origin of guanidine:
1860–65; guan (o ) + -idine
A strong base HN=C(NH) obtained by the oxidation of guanine
a strongly alkaline base, CN3H5, formed by the oxidation of guanin, and also obtained combined with methyl in the decomposition of creatin. Boiled with dilute sulphuric acid, it yields urea and ammonia
Guanidine is a crystalline compound of strong alkalinity formed by the oxidation of guanine. It is used in the manufacture of plastics and explosives. It is found in urine as a normal product of protein metabolism. The molecule was first synthesized in 1861 by the oxidative degradation of an aromatic natural product, guanine, isolated from Peruvian guano. X-ray crystallographic data of adducts of guanidine were revealed in 2007 but the full crystal structure of guanidine was first elucidated 148 years after its first synthesis, despite the simplicity of the molecule. In the year 2013, the positions of the hydrogen atoms and their displacement parameters were accurately determined using single-crystal neutron diffraction. Guanidine is probably most easily recognized as the functional group of arginine and its structure can be thought of as a nitrogenous analogue of the carbonate functional group.
U.S. National Library of Medicine
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
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