Definitions of gtp-binding protein alpha subunits

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Definition of 'gtp-binding protein alpha subunits'

U.S. National Library of Medicine

1. gtp-binding protein alpha subunits
The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the heterotrimeric complex these subunits interact with a variety of second messenger systems. Hydrolysis of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The GTP-Binding protein alpha subunits are grouped into families according to the type of action they have on second messenger systems.

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