Definitions for glandersˈglæn dərz
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a destructive and contagious bacterial disease of horses that can be transmitted to humans
An infectious disease of horses, mules and donkeys caused by the bacterium Burkholderia, one species of which may be transmitted to humans.
a highly contagious and very destructive disease of horses, asses, mules, etc., characterized by a constant discharge of sticky matter from the nose, and an enlargement and induration of the glands beneath and within the lower jaw. It may transmitted to dogs, goats, sheep, and to human beings
Origin: [From Gland.]
Glanders is an infectious disease that occurs primarily in horses, mules, and donkeys. It can be contracted by other animals such as dogs, cats and goats. It is caused by infection with the bacterium Burkholderia mallei, usually by ingestion of contaminated food or water. Signs of glanders include the formation of nodular lesions in the lungs and ulceration of the mucous membranes in the upper respiratory tract. The acute form results in coughing, fever and the release of an infectious nasal discharge, followed by septicaemia and death within days. In the chronic form, nasal and subcutaneous nodules develop, eventually ulcerating. Death can occur within months, while survivors act as carriers. Glanders is endemic in Africa, Asia, the Middle East, Central and South America. It has been eradicated from North America, Australia and most of Europe through surveillance and destruction of affected animals, and import restrictions. Burkholderia mallei is able to infect humans and is therefore classed as a zoonotic agent. Transmission occurs by direct contact with infected animals and entry is through skin abrasions, nasal and oral mucosal surfaces, or by inhalation.
U.S. National Library of Medicine
A contagious disease of horses that can be transmitted to humans. It is caused by BURKHOLDERIA MALLEI and characterized by ulceration of the respiratory mucosa and an eruption of nodules on the skin.
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