Definitions of gene therapy [ʒəˈneɪ]

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Definition of 'gene therapy'

Random House Webster's College Dictionary

1. (n.) gene therapy
the treatment of a disease by replacing aberrant genes with normal ones, esp. through the use of viruses to transport the desired genes into the nuclei of blood cells.

Etymology: (1970–75)

Definition of 'gene therapy'

U.S. National Library of Medicine

1. gene therapy
The introduction of new genes into cells for the purpose of treating disease by restoring or adding gene expression. Techniques include insertion of retroviral vectors, transfection, homologous recombination, and injection of new genes into the nuclei of single cell embryos. The entire gene therapy process may consist of multiple steps. The new genes may be introduced into proliferating cells in vivo (e.g., bone marrow) or in vitro (e.g., fibroblast cultures) and the modified cells transferred to the site where the gene expression is required. Gene therapy may be particularly useful for treating enzyme deficiency diseases, hemoglobinopathies, and leukemias and may also prove useful in restoring drug sensitivity, particularly for leukemia.

'gene therapy' - Nearby Entries
gene regulatory networks gene silencing gene targeting gene therapy gene transfer techniques gene transfer, horizontal general adaptation syndrome

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