Definitions for gangliosidoses, gm2

This page provides all possible meanings and translations of the word gangliosidoses, gm2

U.S. National Library of Medicine

  1. Gangliosidoses, GM2

    A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.

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