An amino acid found in the nervous systems of vertebrates and acting as an inhibitory neurotransmitter. Abbreviated as GABA.
γ-Aminobutyric acid is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.
U.S. National Library of Medicine
The most common inhibitory neurotransmitter in the central nervous system.
Is a primary neurotransmitter in the brain and nervous system of an animal, human and mammal. It is also found in a number of insect and plants.
Gamma-aminobutyric acid was first synthesized in 1883, and was first known only as a plant and microbe metabolic product. In 1950, however, GABA was discovered to be an integral part of the mammalian central nervous system.
The numerical value of gamma-aminobutyric acid in Chaldean Numerology is: 5
The numerical value of gamma-aminobutyric acid in Pythagorean Numerology is: 4
Images & Illustrations of gamma-aminobutyric acid
Find a translation for the gamma-aminobutyric acid definition in other languages:
Select another language:
Discuss these gamma-aminobutyric acid definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"gamma-aminobutyric acid." Definitions.net. STANDS4 LLC, 2017. Web. 22 Nov. 2017. <http://www.definitions.net/definition/gamma-aminobutyric acid>.