Definitions for fusion proteins, bcr-abl
This page provides all possible meanings and translations of the word fusion proteins, bcr-abl
U.S. National Library of Medicine
Fusion Proteins, bcr-abl
Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. The p210(bcr-abl) fusion protein is found in patients with LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE. The p190(bcr-abl) fusion protein is found in patients with PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in ABELSON MURINE LEUKEMIA VIRUS.
Find a translation for the fusion proteins, bcr-abl definition in other languages:
Select another language:
Discuss these fusion proteins, bcr-abl definitions with the community:
Use the citation below to add this definition to your bibliography:
"fusion proteins, bcr-abl." Definitions.net. STANDS4 LLC, 2014. Web. 20 Sep. 2014. <http://www.definitions.net/definition/fusion proteins, bcr-abl>.