Definitions for focal adhesion kinase 1
This page provides all possible meanings and translations of the word focal adhesion kinase 1
U.S. National Library of Medicine
Focal Adhesion Kinase 1
A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.
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"focal adhesion kinase 1." Definitions.net. STANDS4 LLC, 2014. Web. 9 Mar. 2014. <http://www.definitions.net/definition/focal adhesion kinase 1>.