Definitions for focal adhesion kinase 1
This page provides all possible meanings and translations of the word focal adhesion kinase 1
U.S. National Library of Medicine
Focal Adhesion Kinase 1
A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.
Find a translation for the focal adhesion kinase 1 definition in other languages:
Select another language:
Discuss these focal adhesion kinase 1 definitions with the community:
Use the citation below to add this definition to your bibliography:
"focal adhesion kinase 1." Definitions.net. STANDS4 LLC, 2014. Web. 20 Oct. 2014. <http://www.definitions.net/definition/focal adhesion kinase 1>.