Definitions for focal adhesion kinase 1
This page provides all possible meanings and translations of the word focal adhesion kinase 1
U.S. National Library of Medicine
Focal Adhesion Kinase 1
A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.
Find a translation for the focal adhesion kinase 1 definition in other languages:
Select another language:
Discuss these focal adhesion kinase 1 definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"focal adhesion kinase 1." Definitions.net. STANDS4 LLC, 2015. Web. 27 Apr. 2015. <http://www.definitions.net/definition/focal adhesion kinase 1>.