Definitions for focal adhesion kinase 1

This page provides all possible meanings and translations of the word focal adhesion kinase 1

U.S. National Library of Medicine

  1. Focal Adhesion Kinase 1

    A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.

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"focal adhesion kinase 1." Definitions.net. STANDS4 LLC, 2015. Web. 3 Jul 2015. <http://www.definitions.net/definition/focal adhesion kinase 1>.

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