U.S. National Library of Medicine
Focal Adhesion Kinase 1
A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.
The numerical value of focal adhesion kinase 1 in Chaldean Numerology is: 7
The numerical value of focal adhesion kinase 1 in Pythagorean Numerology is: 9
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"focal adhesion kinase 1." Definitions.net. STANDS4 LLC, 2018. Web. 21 Jan. 2018. <http://www.definitions.net/definition/focal adhesion kinase 1>.