Definitions for excipientɪkˈsɪp i ənt
This page provides all possible meanings and translations of the word excipient
Random House Webster's College Dictionary
ex•cip•i•entɪkˈsɪp i ənt(n.)
any pharmacologically inert substance used for combining with a drug for the desired bulk, consistency, etc.
Origin of excipient:
1745–55; < L excipient-, s. of excipiēns, prp. of excipere to receive, absorb, lit., to take out; see except1
An ingredient that is intentionally added to a drug for purposes other than the therapeutic or diagnostic effect at the intended dosage.
taking an exception
an inert or slightly active substance used in preparing remedies as a vehicle or medium of administration for the medicinal agents
An excipient is generally a pharmacologically inactive substance formulated with the active ingredient of a medication. Excipients are commonly used to bulk up formulations that contain potent active ingredients, to allow convenient and accurate dispensation of a drug substance when producing a dosage form. They also can serve various therapeutic-enhancing purposes, such as facilitating drug absorption or solubility, or other pharmacokinetic considerations. Excipients can also be useful in the manufacturing process, to aid in the handling of the active substance concerned such as by facilitating powder flowability or non-stick properties, in addition to aiding in vitro stability such as prevention of denaturation over the expected shelf life. The selection of appropriate excipients also depends upon the route of administration and the dosage form, as well as the active ingredient and other factors. Pharmaceutical regulations and standards require that all ingredients in drugs, as well as their chemical decomposition products, be identified and shown to be safe. As with new drug substances and dosage forms thereof, novel excipients themselves can be patented; sometimes, however, a particular formulation involving them is kept as a trade secret instead.
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