Definitions for etoposide

This page provides all possible meanings and translations of the word etoposide

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  1. etoposide(Noun)

    A derivative of podophyllotoxin that is used in the treatment of some cancers by inhibiting mitosis

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  1. Etoposide

    Etoposide, etoposide phosphate or VP-16 is a cytotoxic agent, which belongs to the drug type topoisomerase inhibitor.

U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)

  1. Etoposide

    A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

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