What does epitope mean?

Definitions for epitope
ˈɛp ɪˌtoʊpepi·tope

This dictionary definitions page includes all the possible meanings, example usage and translations of the word epitope.

Princeton's WordNet

  1. antigenic determinant, determinant, epitopenoun

    the site on the surface of an antigen molecule to which an antibody attaches itself

Wiktionary

  1. epitopenoun

    That part of a biomolecule (such as a protein) that is the target of an immune response

Wikipedia

  1. Epitope

    An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. The part of an antibody that binds to the epitope is called a paratope. Although epitopes are usually non-self proteins, sequences derived from the host that can be recognized (as in the case of autoimmune diseases) are also epitopes.The epitopes of protein antigens are divided into two categories, conformational epitopes and linear epitopes, based on their structure and interaction with the paratope. Conformational and linear epitopes interact with the paratope based on the 3-D conformation adopted by the epitope, which is determined by the surface features of the involved epitope residues and the shape or tertiary structure of other segments of the antigen. A conformational epitope is formed by the 3-D conformation adopted by the interaction of discontiguous amino acid residues. In contrast, a linear epitope is formed by the 3-D conformation adopted by the interaction of contiguous amino acid residues. A linear epitope is not determined solely by the primary structure of the involved amino acids. Residues that flank such amino acid residues, as well as more distant amino acid residues of the antigen affect the ability of the primary structure residues to adopt the epitope's 3-D conformation. 90% of epitopes are conformational.

ChatGPT

  1. epitope

    An epitope, also known as an antigenic determinant, is the specific part of an antigen that is recognized and bound by an antibody. This binding can trigger an immune response. Epitopes can be part of proteins, polysaccharides, nucleic acids, or lipids on the surface of pathogens like bacteria, viruses, or other foreign substances in the body.

Wikidata

  1. Epitope

    An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. The part of an antibody that recognizes the epitope is called a paratope. Although epitopes are usually non-self proteins, sequences derived from the host that can be recognized are also epitopes. The epitopes of protein antigens are divided into two categories, conformational epitopes and linear epitopes, based on their structure and interaction with the paratope. A conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. Most epitopes are conformational. By contrast, linear epitopes interact with the paratope based on their primary structure. A linear epitope is formed by a continuous sequence of amino acids from the antigen.

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Numerology

  1. Chaldean Numerology

    The numerical value of epitope in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of epitope in Pythagorean Numerology is: 5

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"epitope." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/epitope>.

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