What does enhanceosome mean?
Definitions for enhanceosome
en·hanceo·some
This dictionary definitions page includes all the possible meanings, example usage and translations of the word enhanceosome.
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Wiktionary
enhanceosomenoun
A protein complex that binds to the enhancer region of a gene
Wikidata
Enhanceosome
The enhanceosome is a protein complex that binds to the "enhancer" region of a gene, found upstream or downstream, of the promoter, or within a gene. It accelerates the gene's transcription. The binding and assembly of the activating proteins, some of which may be transcription factors, is cooperative due to energetically favorable protein-protein interactions formed in the complex. The best known example of the enhanceosome acts on the human interferon-beta gene, which is upregulated in cells that are infected by viruses. Three activator proteins - NF-κB, an interferon activator protein such as IRF-3, and the ATF-2/c-Jun complex - cooperatively bind to the upstream enhancer region upon viral infection. The interaction is mediated by a fourth protein HMG-I, which assists in stabilizing the complex by promoting inter-protein interactions. The assembled enhanceosome recruits transcriptional machinery such as RNA polymerase to the promoter region to initiate gene expression.
Numerology
Chaldean Numerology
The numerical value of enhanceosome in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of enhanceosome in Pythagorean Numerology is: 9
Translations for enhanceosome
From our Multilingual Translation Dictionary
- ενισχυόσωμαGreek
- realceosomaSpanish
- enhanceosomeItalian
- enhanceosomeDutch
- potenciassomaPortuguese
- tăng cườngVietnamese
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"enhanceosome." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/enhanceosome>.
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