Definitions for endotoxin
ˌɛn doʊˈtɒk sɪnen·do·tox·in

Princeton's WordNetRate this definition:0.0 / 0 votes

1. endotoxinnoun

   a toxin that is confined inside the microorganisms and is released only when the microorganisms are broken down or die

WiktionaryRate this definition:0.0 / 0 votes

1. endotoxinnoun

   Any toxin secreted by a microorganism and released into the surrounding environment only when it dies.

WikipediaRate this definition:0.0 / 0 votes

1. endotoxin

   Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide that are bacterial toxins. They are composed of an O-antigen, an outer core, and an inner core all joined by a covalent bond, and are found in the outer membrane of Gram-negative bacteria. Today, the term endotoxin is often used synonymously with LPS, although there are a few endotoxins (in the original sense of toxins that are inside the bacterial cell that are released when the cell disintegrates) that are not related to LPS, such as the so-called delta endotoxin proteins produced by Bacillus thuringiensis.Lipopolysaccharides can have substantial impacts on human health, primarily through interactions with the immune system. LPS is a potent activator of the immune system and pyrogen (agent that causes fever). In severe cases, LPS can play a role in causing septic shock. In lower levels and over a longer time period, there is evidence LPS may play an important and harmful role in autoimmunity, obesity, depression, and cellular senescence.

ChatGPTRate this definition:0.0 / 0 votes

1. endotoxin

   An endotoxin is a toxic substance that is released when certain bacteria, particularly gram-negative bacteria, are destroyed or disintegrate. The primary type of endotoxins are lipopolysaccharides found in the outer cell membrane. Endotoxins can cause a strong immune response, leading to severe health issues like septic shock.

WikidataRate this definition:0.0 / 0 votes

1. Endotoxin

   The term endotoxin was coined by Richard Friedrich Johannes Pfeiffer, who distinguished between exotoxin, which he classified as a toxin that is released by bacteria into the environment, and endotoxin, which he considered to be a toxin kept "within" the bacterial cell and to be released only after destruction of the bacterial cell wall. Today, the term 'endotoxin' is used synonymously with the term lipopolysaccharide., which is a major constituent of the outer cell membrane of Gram-negative bacteria. Larger amounts of endotoxins can be mobilized if Gram-negative bacteria are killed or destroyed by detergents. The term "endotoxin" came from the discovery that portions of Gram-negative bacteria themselves can cause toxicity. Studies of endotoxin over the next 50 years revealed that the effects of "endotoxin" are, in fact, due to lipopolysaccharide. The key effects of endotoxins on vertebrates are mediated by their interaction with specific receptors on immune cells such as monocytes, macrophages, dendritic cells, and others. Upon challenge with endotoxin, these cells form a broad spectrum of immune mediators such as cytokines, nitric oxide, and eicosanoids.

Matched Categories

1. • Toxin

How to pronounce endotoxin?

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Numerology

1. Chaldean Numerology

   The numerical value of endotoxin in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of endotoxin in Pythagorean Numerology is: 3

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=endotoxin
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Endotoxin
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Endotoxin
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=endotoxin