Definitions of edar-associated death domain protein

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Definition of 'edar-associated death domain protein'

U.S. National Library of Medicine

1. edar-associated death domain protein
A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.

'edar-associated death domain protein' - Nearby Entries
ectromelia, infectious eczema, dyshidrotic edar receptor edar-associated death domain protein edeine edema disease of swine edema, cardiac

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