Definitions for e2f6 transcription factor

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U.S. National Library of Medicine

  1. E2F6 Transcription Factor

    An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.

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