U.S. National Library of Medicine
Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.
The numerical value of dna damage in Chaldean Numerology is: 1
The numerical value of dna damage in Pythagorean Numerology is: 5
Sample Sentences & Example Usage
We have to understand the mechanisms, so we can selectively provide good therapy, we can't avoid DNA damage. We live in a world where we get exposed to DNA damaging agents all the time.
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