Definitions for diproqualone
dipro·qualone

WiktionaryRate this definition:0.0 / 0 votes

1. diproqualonenoun

   A synthetic analogue of methaqualone with sedative, anxiolytic, antihistamine and analgesic properties.

WikipediaRate this definition:0.0 / 0 votes

1. Diproqualone

   Diproqualone is a quinazolinone class GABAergic and is an analogue of methaqualone developed in the late 1950s by a team at Nogentaise de Produits Chimique. It was marketed primarily in France and some other European countries. It has sedative, anxiolytic, antihistamine and analgesic properties, resulting from its agonist activity at the β subtype of the GABAa receptor, antagonist activity at all histamine receptors, inhibition of the cyclooxygenase-1 enzyme, and possibly its agonist activity at both the sigma-1 receptor and sigma-2 receptor (the function of these receptors and their clinical relevance has not yet been determined). Diproqualone is used primarily for the treatment of inflammatory pain associated with osteoarthritis and rheumatoid arthritis, and more rarely for treating insomnia, anxiety and neuralgia. Diproqualone is the only analogue of methaqualone that is still in widespread clinical use, due to its useful anti-inflammatory and analgesic effects in addition to the sedative and anxiolytic actions common to other drugs of this class. There are still some concerns about the potential of diproqualone for abuse and overdose, and so it is not sold as a pure drug but only as the camphosulfonate salt in combination mixtures with other medicines such as ethenzamide.

WikidataRate this definition:0.0 / 0 votes

1. Diproqualone

   Diproqualone is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative, anxiolytic, antihistamine and analgesic properties, and is used primarily for the treatment of inflammatory pain associated with osteoarthritis and rheumatoid arthritis, and more rarely for treating insomnia, anxiety and neuralgia. Diproqualone is the only analogue of methaqualone that is still in widespread clinical use, due to its useful anti-inflammatory and analgesic effects in addition to the sedative and anxiolytic actions common to other drugs of this class. There are still some concerns about the potential of diproqualone for abuse and overdose, and so it is not sold as a pure drug but only as the camphosulfonate salt in combination mixtures with other medicines such as ethenzamide.

How to pronounce diproqualone?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say diproqualone in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of diproqualone in Chaldean Numerology is: 5

2. Pythagorean Numerology

   The numerical value of diproqualone in Pythagorean Numerology is: 3

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Diproqualone
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Diproqualone
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=diproqualone