Definitions for dax-1 orphan nuclear receptor

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U.S. National Library of Medicine

  1. DAX-1 Orphan Nuclear Receptor

    An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.

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