Definitions for dapsoneˈdæp soʊn
This page provides all possible meanings and translations of the word dapsone
Random House Webster's College Dictionary
an antibacterial substance, C12H12N2O2S, used to treat leprosy.
Origin of dapsone:
1965–70; d(i)a(minodi)p(henyl) s(ulf)one
antibacterial drug used to treat leprosy and some kinds of skin diseases
A drug, 4-[(4-aminobenzene)sulfonyl]aniline, used in the treatment of leprosy and similar infections
Dapsone is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy for the treatment of Mycobacterium leprae infections. It is also second-line treatment for prophylaxis against Pneumocystis pneumonia caused by Pneumocystis jirovecii in HIV patients in whom CD4 counts are below 200/mm³. Dapsone is an odorless white to creamy-white crystalline powder with a slightly bitter taste, used in combination with pyrimethamine in the treatment of malaria. Dapsone is commercially available in both topical and oral formulations. Topical dapsone is available in a 5% gel formulation that is sold under the brand name Aczone and is produced by Allergan. Oral dapsone is also available but is less commonly used than other sulfonamide antibiotics, many of which have a lower incidence of adverse effects.
U.S. National Library of Medicine
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
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