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1. (n.) cystic fibrosis
a hereditary disease of the exocrine glands characterized by the production of thickened mucus that chronically clogs the bronchi and pancreatic ducts, leading to breathing difficulties, infection, and fibrosis.
Etymology: (1950–55)
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| Definition of 'cystic fibrosis' |
Princeton's WordNet |
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1. (noun) cystic fibrosis, CF, fibrocystic disease of the pancreas, pancreatic fibrosis, mucoviscidosis
the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
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| Definition of 'cystic fibrosis' |
U.S. National Library of Medicine |
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1. cystic fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
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Definitions of cystic fibrosis 
