Definitions for cradd signaling adaptor protein

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U.S. National Library of Medicine

  1. CRADD Signaling Adaptor Protein

    A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.

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