What does complexin mean?

Definitions for complexin
com·plex·in

This dictionary definitions page includes all the possible meanings, example usage and translations of the word complexin.


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Wiktionary

  1. complexinnoun

    A type of protein found in nerve tissue.

Wikidata

  1. Complexin

    In molecular biology, complexin, a eukaryotic specific protein, is a cytoplasmic neuronal protein which binds to the SNARE protein complex with a high affinity. In the presence of Ca2+, the transport vesicle protein synaptotagmin displaces complexin, allowing the SNARE protein complex to bind the transport vesicle to the presynaptic membrane. Complexin acts as both an inhibitor and a facilitator of synaptic vesicle fusion and neurotransmitter release. In one conformation, it clamps SNAREpin complexes, preventing vesicle fusion, while in a different conformation it releases the SNAREpins, allowing synaptotagmin to trigger fusion. Whereas complexin is not necessary for synaptic vesicle exocytosis, it does increase neurotransmitter release by 60–70% as demonstrated by complexin gene knockout in mice A number of human neurological diseases have been linked to a deficiency of complexin.

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Numerology

  1. Chaldean Numerology

    The numerical value of complexin in Chaldean Numerology is: 5

  2. Pythagorean Numerology

    The numerical value of complexin in Pythagorean Numerology is: 3

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"complexin." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/complexin>.

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