Definitions for clofazimine
clo·faz·imine

WiktionaryRate this definition:0.0 / 0 votes

1. clofaziminenoun

   A fat-soluble riminophenazine dye used to treat leprosy.

WikipediaRate this definition:0.0 / 0 votes

1. Clofazimine

   Clofazimine, sold under the brand name Lamprene, is a medication used together with rifampicin and dapsone to treat leprosy. It is specifically used for multibacillary (MB) leprosy and erythema nodosum leprosum. Evidence is insufficient to support its use in other conditions though a retrospective study found it 95% effective in the treatment of Mycobacterium avium complex (MAC) when administered with a macrolide and ethambutol, as well as the drugs amikacin and clarithromycin. However, in the United States, clofazimine is considered an orphan drug, is unavailable in pharmacies, and its use in the treatment of MAC is overseen by the Food and Drug Administration. It is taken orally.Common side effects include abdominal pain, diarrhea, itchiness, dry skin, and change in skin color. It can also cause swelling of the lining of the gastrointestinal tract, increased blood sugar, and sensitivity to the sun. It is unclear if use during pregnancy is safe. Clofazimine is a phenazine dye and is believed to work by interfering with DNA.Clofazimine was discovered in the 1950s at Trinity College, Dublin, and approved for medical use in the United States in 1986. It is on the World Health Organization's List of Essential Medicines. In the United States it is not available commercially but can be obtained from the US Department of Health and Human Services.

WikidataRate this definition:0.0 / 0 votes

1. Clofazimine

   Clofazimine is a fat-soluble riminophenazine dye used in combination with rifampicin and dapsone as multidrug therapy for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients and Mycobacterium avium paratuberculosis infection in Crohn's disease patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum.. The drug is given as an alternative to patients who can not tolerate the effects of dapsone for tuberculosis.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Clofazimine

   A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)

How to pronounce clofazimine?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say clofazimine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of clofazimine in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of clofazimine in Pythagorean Numerology is: 5

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Clofazimine
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Clofazimine
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=clofazimine