Definitions for chronic lymphocytic leukemia
chron·ic lympho·cyt·ic leukemi·a

Princeton's WordNetRate this definition:0.0 / 0 votes

1. chronic lymphocytic leukemianoun

   chronic leukemia characterized by lymphoblast-like cells; more common in older men

WikipediaRate this definition:0.0 / 0 votes

1. Chronic lymphocytic leukemia

   Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). Early on, there are typically no symptoms. Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur. Enlargement of the spleen and low red blood cells (anemia) may also occur. It typically worsens gradually over years.Risk factors include having a family history of the disease, with 10% of those who develop CLL having a family history of the disease. Exposure to Agent Orange, certain insecticides, sun exposure, exposure to hepatitis C virus, and common infections are also considered risk factors. CLL results in the buildup of B cell lymphocytes in the bone marrow, lymph nodes, and blood. These cells do not function well and crowd out healthy blood cells. CLL is divided into two main types: those with a mutated IGHV gene and those without. Diagnosis is typically based on blood tests finding high numbers of mature lymphocytes and smudge cells.Early-stage CLL in asymptomatic cases responds better to careful observation, as there is no evidence that early intervention treatment can alter the course of the disease. Immune defects occur early in the course of CLL and these increase the risk of developing serious infection, which should be treated appropriately with antibiotics. In those with significant symptoms, chemotherapy, immunotherapy, or chemoimmunotherapy may be used. Depending on the individual's age, physical condition, and whether they have the del(17p) or TP53 mutation, different first line treatments may be offered. As of 2021, BTK inhibitors such as ibrutinib and acalabrutinib are often recommended for first line treatment of CLL. The medications fludarabine, cyclophosphamide, and rituximab were previously the initial treatment in those who are otherwise healthy.CLL affected about 904,000 people globally in 2015 and resulted in 60,700 deaths. In 2021, the estimated incidence of CLL in the United States is 21,250 new cases and 4,320 deaths. The disease most commonly occurs in people over the age of 65, due to the accumulation of genetic mutations that occurs over time. Men are diagnosed around twice as often as women (6.8 to 3.5 ratio). It is much less common in people from Asia. Five-year survival following diagnosis is approximately 83% in the United States. It represents less than 1% of deaths from cancer.

ChatGPTRate this definition:0.0 / 0 votes

1. chronic lymphocytic leukemia

   Chronic Lymphocytic Leukemia (CLL) is a type of cancer that originates in the bone marrow and results in the excessive production of abnormal or immature lymphocytes, which are a type of white blood cells. It is characterized by its slow progression, as the word 'chronic' indicates. These excessive lymphocytes may compromise the immune system, reducing the body's ability to fight infection and potentially leading to anemia and other serious conditions. CLL is most commonly diagnosed in adults over the age of 60.

Matched Categories

1. • Chronic Leukemia

How to pronounce chronic lymphocytic leukemia?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say chronic lymphocytic leukemia in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of chronic lymphocytic leukemia in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of chronic lymphocytic leukemia in Pythagorean Numerology is: 8

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=chronic lymphocytic leukemia
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Chronic_Lymphocytic_Leukemia
3. ^ ChatGPT
   https://chat.openai.com