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 Definitions of charcot-marie-tooth disease  

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Definition of 'charcot-marie-tooth disease' Princeton's WordNet 

1. (noun) Charcot-Marie-Tooth disease, hereditary motor and sensory neuropathy
a form of neuropathy that can begin between childhood and young adulthood; characterized by weakness and atrophy of the muscles of the hands and lower legs; progression is slow and individuals affected can have a normal life span; inheritance is X-linked recessive or X-linked dominant


Definition of 'charcot-marie-tooth disease' U.S. National Library of Medicine 

1.  charcot-marie-tooth disease
A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)



'charcot-marie-tooth disease' - Nearby Entries  

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