Definition of charcot-marie-tooth disease

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1. (noun) Charcot-Marie-Tooth disease, hereditary motor and sensory neuropathy
a form of neuropathy that can begin between childhood and young adulthood; characterized by weakness and atrophy of the muscles of the hands and lower legs; progression is slow and individuals affected can have a normal life span; inheritance is X-linked recessive or X-linked dominant

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