Definitions for bumetanide
bumetanide

WiktionaryRate this definition:0.0 / 0 votes

1. bumetanidenoun

   A sulfamyl drug used to treat heart failure.

WikipediaRate this definition:0.0 / 0 votes

1. Bumetanide

   Bumetanide, sold under the brand name Bumex among others, is a medication used to treat swelling and high blood pressure. This includes swelling as a result of heart failure, liver failure, or kidney problems. It may work for swelling when other medications have not. For high blood pressure it is not a preferred treatment. It is taken by mouth, or by injection into a vein or muscle. Effects generally begin within an hour and lasts for about six hours.Common side effects include dizziness, low blood pressure, low blood potassium, muscle cramps, and kidney problems. Other serious side effects may include hearing loss and low blood platelets. Blood tests are recommended regularly for those on treatment. Safety during pregnancy and breastfeeding is unclear. Bumetanide is a loop diuretic and works by decreasing the reabsorption of sodium by the kidneys.Bumetanide was patented in 1968 and came into medical use in 1972. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 270th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

ChatGPTRate this definition:0.0 / 0 votes

1. bumetanide

   Bumetanide is a medication used to treat fluid retention (edema) resulting from conditions such as heart failure, liver disease, or kidney disease. It belongs to a class of drugs known as loop diuretics, which work by increasing the amount of urine produced by the kidneys. This helps to decrease swelling and reduce the excess fluid in the body.

WikidataRate this definition:0.0 / 0 votes

1. Bumetanide

   Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in people in whom high doses of furosemide are ineffective. It is marketed by Hoffmann-La Roche. The main difference between the two substances is in bioavailability and pharmacodynamic potency. Furosemide is incompletely absorbed in the intestine, and there is substantial inter- and intraindividual differences in bioavailability. Bumetanide is almost completely absorbed, and the absorption is not altered when it is taken with food. It is said to be a more predictable diuretic, meaning that the predictable absorption is reflected in a more predictable effect. Bumetanide is 40 times more potent than furosemide. In the brain, bumetanide blocks the NKCC1 cation-chloride co-transporter, and thus decreases internal chloride concentration in neurons. In turn, this concentration change makes the action of GABA more hyperpolarizing, which may be useful for treatment of neonatal seizures, that quite often are not responsive to traditional GABA-targeted treatment, such as barbiturates. Bumetanide is therefore currently under evaluation as a prospective antiepileptic drug.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Bumetanide

   A sulfamyl diuretic.

How to pronounce bumetanide?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

   British

   Mia

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   Karen

   Australian

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   Australian

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   Indian

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   Neerja

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   Zira

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   South African

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Numerology

1. Chaldean Numerology

   The numerical value of bumetanide in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of bumetanide in Pythagorean Numerology is: 4

Popularity rank by frequency of use

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Bumetanide
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Bumetanide
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=bumetanide