Definitions for biomarker
biomark·er

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1. biomarkernoun

   A substance used as an indicator of a biological state, most commonly disease.

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1. Biomarker

   In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. Biomarkers are used in many scientific fields.

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1. Biomarker

   In medicine, a biomarker is a measurable characteristic that reflects the severity or presence of some disease state. More generally a biomarker is anything that can be used as an indicator of a particular disease state or some other physiological state of an organism. A biomarker can be a substance that is introduced into an organism as a means to examine organ function or other aspects of health. For example, rubidium chloride is used as a radioactive isotope to evaluate perfusion of heart muscle. It can also be a substance whose detection indicates a particular disease state, for example, the presence of an antibody may indicate an infection. More specifically, a biomarker indicates a change in expression or state of a protein that correlates with the risk or progression of a disease, or with the susceptibility of the disease to a given treatment. Biomarkers are characteristic biological properties that can be detected and measured in parts of the body like the blood or tissue. They may indicate either normal or diseased processes in the body. Biomarkers can be specific cells, molecules, or genes, gene products, enzymes, or hormones. Complex organ functions or general characteristic changes in biological structures can also serve as biomarkers. Although the term biomarker is relatively new, biomarkers have been used in pre-clinical research and clinical diagnosis for a considerable time. For example, body temperature is a well-known biomarker for fever. Blood pressure is used to determine the risk of stroke. It is also widely known that cholesterol values are a biomarker and risk indicator for coronary and vascular disease, and that C-reactive protein is a marker for inflammation.

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How to say biomarker in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of biomarker in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of biomarker in Pythagorean Numerology is: 2

Examples of biomarker in a Sentence

1. Richard Isaacson:

   Most physicians believe in the power of exercise to support overall brain health, but fewer believe that exercise can specifically impact people with early Alzheimer's, this study brings us one step closer toward teasing out the effects in people with biomarker defined Alzheimer's.

2. Daniel Belsky:

   This is not a game over moment. It’s more like game on, what we have now is a proof of concept — a methylation biomarker that shows faster aging in people we know to be at higher risk for disease, disability and death, and slower aging in people who we know to be at lower risk.

3. Brooks Gump:

   Even though they're not dying from that cardiac injury, something about that biomarker is providing some prognostic value beyond other risk factors that were controlled, so it could still be important in terms of identifying high-risk patients that enter the hospital with Covid-19.

4. David Tester:

   Having this genetic biomarker, we can now very easily test any individual for the presence of the mutation, having that ability can potentially save lives.

5. Richard Isaacson:

   Neuroticism is specifically one trait that comes to mind, and past meta-analyses have also show this. Rumination and worry is linked to smaller brain volumes, it's unclear if the stress/neuroinflammation pathway drives this. A biomarker doesn't really exist for this so it's hard to prove.

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Biomarker
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Biomarker
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=biomarker