Definitions for biofilm
This page provides all possible meanings and translations of the word biofilm
A complex aggregation of microorganisms marked by the excretion of a protective and adhesive matrix.
A biofilm is any group of microorganisms in which cells stick to each other on a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance. Biofilm EPS, which is also referred to as slime, is a polymeric conglomeration generally composed of extracellular DNA, proteins, and polysaccharides. Biofilms may form on living or non-living surfaces and can be prevalent in natural, industrial and hospital settings. The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single-cells that may float or swim in a liquid medium. Microbes form a biofilm in response to many factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics. When a cell switches to the biofilm mode of growth, it undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated.
Sample Sentences & Example Usage
We were going from a mature, established population of a few billion cells, all stuck together in this highly protected biofilm coat, to really just a few thousand cells left alive. This is a massive, massive killing ability.
The results show that after the use of oral antimicrobials, a shift occurs in the composition of the oral biofilm in a more healthy direction. Several species that can cause caries such as S. Mutans and Lactobacillus, decrease in prevalence, whereas the more harmless species increase in prevalence.
What we found was very interesting -- we found that Bald's eyesalve is incredibly potent as an anti-Staphylococcal antibiotic in this context, we were going from a mature, established population of a few billion cells, all stuck together in this highly protected biofilm coat, to really just a few thousand cells left alive. This is a massive, massive killing ability.
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