What does bevacizumab mean?
Definitions for bevacizumab
be·va·cizum·ab
This dictionary definitions page includes all the possible meanings, example usage and translations of the word bevacizumab.
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Wiktionary
bevacizumabnoun
A monoclonal antibody used in the treatment of cancer.
Wikidata
Bevacizumab
Bevacizumab is an angiogenesis inhibitor, a drug that slows the growth of new blood vessels. It is licensed to treat various cancers, including colorectal, lung, breast, glioblastoma, kidney and ovarian. Bevacizumab is a humanized monoclonal antibody that inhibits vascular endothelial growth factor A. VEGF-A is a chemical signal that stimulates angiogenesis in a variety of diseases, especially in cancer. Bevacizumab was the first clinically available angiogenesis inhibitor in the United States. Bevacizumab was approved by the U.S. Food and Drug Administration for certain metastatic cancers. It received its first approval in 2004, for combination use with standard chemotherapy for metastatic colon cancer. It has since been approved for use in certain lung cancers, renal cancers, and glioblastoma multiforme of the brain. At one point bevacizumab was approved for breast cancer by the FDA, but the approval was revoked on 18 November 2011. The approval for breast cancer was revoked because, although there was evidence that it slowed progression of metastatic breast cancer, there was no evidence that it extended life or improved quality of life, and it caused adverse effects including severe high blood pressure and hemorrhaging. In 2008, the FDA gave bevacizumab provisional approval for metastatic breast cancer, subject to further studies. The FDA's advisory panel had recommended against approval. In July 2010, after new studies failed to show a significant benefit, the FDA's advisory panel recommended against the indication for advanced breast cancer. Genentech requested a hearing, which was granted in June 2011. The FDA ruled to withdraw the breast cancer indication in November 2011. FDA approval is required for Genentech to market a drug for that indication. Doctors may sometimes prescribe it for that indication, although insurance companies are less likely to pay for it. The drug remains approved for breast cancer use in other countries including Australia.
Numerology
Chaldean Numerology
The numerical value of bevacizumab in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of bevacizumab in Pythagorean Numerology is: 6
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"bevacizumab." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/bevacizumab>.
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