Definitions for belinostat

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Wiktionary

  1. belinostat(Noun)

    A histone deacetylase inhibitor proposed as an anticancer drug

Freebase

  1. Belinostat

    A novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.

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"belinostat." Definitions.net. STANDS4 LLC, 2014. Web. 23 Sep. 2014. <http://www.definitions.net/definition/belinostat>.

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