What does azaserine mean?
Definitions for azaserine
aza·ser·ine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word azaserine.
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Wikidata
Azaserine
Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent •Description Azaserine is an inhibitor of the rate limiting step of the hexosamine biosynthethic pathway and an irreversible inhibitor of GGT1. Independent of inhibiting the HBP pathway, azarine studies have demonstrated that it can protect against hyperglycemic endothelial damage through its antioxidant effect. Azarine and acivicin, another GGT inhibitor, bind to GGT at its substrate-binding pocket. The compound has been shown to elevate the SOD-2 protein level as well as inhibit the oxidative stress and the expression of VCAM-1 and ICAM-1 in response to TNFα. Research indicates that azaserine has the potential to be used as a probe for identifying the L- system transporter in human T-lymphocytes
U.S. National Library of Medicine
Azaserine
Antibiotic substance produced by various Streptomyces species. It is an inhibitor of enzymatic activities that involve glutamine and is used as an antineoplastic and immunosuppressive agent.
Numerology
Chaldean Numerology
The numerical value of azaserine in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of azaserine in Pythagorean Numerology is: 8
Translations for azaserine
From our Multilingual Translation Dictionary
- azasérineFrench
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"azaserine." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/azaserine>.
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