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1. (n.) atherosclerosis
a common form of arteriosclerosis in which fatty substances form a deposit of plaque on the inner lining of arterial walls.
Etymology: (1905–10; < G Atherosklerose; see athero -, sclerosis)
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| Definition of 'atherosclerosis' |
Princeton's WordNet |
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1. (noun) atherosclerosis, coronary artery disease
a stage of arteriosclerosis involving fatty deposits (atheromas) inside the arterial walls, thus narrowing the arteries
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| Definition of 'atherosclerosis' |
U.S. National Library of Medicine |
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1. atherosclerosis
Thickening and loss of elasticity of the walls of medium and large muscular ARTERIES with lesions in the innermost layer of the artery (ARTERIAL INTIMA). This disease process of atherogenesis includes the retention of cholesterol-rich LIPOPROTEINS and their binding to PROTEOGLYCANS in the arterial intima, generation of proinflammatory molecules that recruit MACROPHAGES to the subendothelial space, formation of FOAM CELLS, and eventual calcification of the arterial wall. These arterial plaques (atheromas) contain CARBOHYDRATES; BLOOD; and CALCIUM.
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