What does asparaginase mean?
Definitions for asparaginase
as·parag·i·nase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word asparaginase.
Princeton's WordNet
asparaginase, Elsparnoun
antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia
Wiktionary
asparaginasenoun
An enzyme that catalyzes the hydrolysis of asparagine to aspartic acid, used in chemotherapy.
Wikipedia
Asparaginase
Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). It is given by injection into a vein, muscle, or under the skin. A pegylated version is also available. In food manufacturing it is used to decrease acrylamide.Common side effects when used by injection include allergic reactions, pancreatitis, blood clotting problems, high blood sugar, kidney problems, and liver dysfunction. Use in pregnancy may harm the baby. As a food it is generally recognized as safe. Asparaginase works by breaking down the amino acid known as asparagine without which the cancer cells cannot make protein.The most common nonhematological adverse reactions of asparaginase erwinia chrysanthemi (recombinant) include abnormal liver test, nausea, musculoskeletal pain, infection, fatigue, headache, febrile neutropenia, pyrexia, hemorrhage (bleeding), stomatitis, abdominal pain, decreased appetite, drug hypersensitivity, hyperglycemia, diarrhea, pancreatitis, and hypokalemia.Asparaginase was approved for medical use in the United States in 1978. It is on the World Health Organization's List of Essential Medicines. It is often made from Escherichia coli (E. coli) or Erwinia chrysanthemi.
ChatGPT
asparaginase
Asparaginase is an enzyme that is used as a medication for its ability to degrade asparagine, an amino acid that is essential for certain types of cancer cells to proliferate. Its primary use is in the treatment of acute lymphoblastic leukemia (ALL), a type of cancer that specifically requires asparagine. It catalyzes the hydrolysis of asparagine to aspartic acid and ammonia, depriving the cancer cells of the asparagine they need to grow and divide.
Wikidata
Asparaginase
Asparaginase is an enzyme that catalyzes the hydrolysis of asparagine to aspartic acid. Asparaginases are naturally occurring enzymes expressed and produced by microorganisms. Colaspase is also known as L-asparaginase.
U.S. National Library of Medicine
Asparaginase
A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of asparaginase in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of asparaginase in Pythagorean Numerology is: 3
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"asparaginase." Definitions.net. STANDS4 LLC, 2024. Web. 19 Mar. 2024. <https://www.definitions.net/definition/asparaginase>.
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