Definitions for arachidonate 5-lipoxygenase

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U.S. National Library of Medicine

Arachidonate 5-Lipoxygenase
An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes. EC 1.13.11.34.

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